师资队伍

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何健/教授

发布时间:2022年10月10日 15:08 | 编辑:成丹 | 作者:

37000cm威尼斯微生物学系教授,博士生导师,入选教育部新世纪优秀人才和江苏省“六大人才高峰”高层次人才计划。中国微生物学会环境微生物专业委员会委员,中国微生物学会资源微生物专业委员会委员。主要从事杀虫剂和除草剂微生物降解菌株和基因资源发掘和降解代谢机制研究。主持国家863项、国家自然科学基金、科技部农业科技成果转化项目、“十二五”农村领域科技计划项目子课题和和江苏省自然科学基金等项目10多项。发现细菌新种30多个,克隆到农药降解/抗性酶新基因20多个,获国家发明专利20余项。通讯作者在Appl. Environ. Microbiol., J. Bacteriol.等SCI刊物上发表论文50余篇。相关成果获得国家科技进步二等奖(排名第五)、农业部农牧渔业丰收奖三等奖(排名第五)和教育部技术发明二等奖(排名第三)。

邮箱:hejian@njau.edu.cn  


教学情况


基础微生物学(研究生)、现代微生物研究技术与方法(研究生)、生物技术(研究生),获得学校优秀班主任称号。



科研情况


近年来主持科研项目情况:

1)  国家自然科学基金项目:定向进化提高磺酰脲除草剂脱毒酯酶SulE催化效率及其机制(31970096,2020-2023)

2)  国家自然科学基金项目:双功能酶Mthfr66的特性及其在四氢叶酸依赖型麦草畏脱甲基途径中的生理功能研究 (31770117, 2018-2021年)

3)  国家自然科学基金项目:四氢叶酸依赖型麦草畏脱甲基酶特性、结构和功能及其应用于抗除草剂转基因工程的可行性研究(31570105, 2016-2019年)

4)  国家自然科学基金项目:国家自然科学基金:Sphingomonas sp. DC-6降解乙草胺的代谢途径及分子机制研究(31270157,2013-2016年)

5)  国家重点研发计划子课题 河网平原区旱地面源污染防控技术集成与示范(2016YFD0801102,2016-2020年)

6)  江苏省科技厅科技攻关项目 麦草畏和磺酰脲类除草剂脱毒酶基因在抗除草剂作物新品种培育中的应用(BE2016374,2016-2019年)

7)  国家“863”项目:菊酯类、磺酰脲类农药残留原位降解技术的研究与应用(2006AA10Z402,2006-2010年)

8)  国家自然科学基金项目:鞘氨醇杆菌JZ-1降解氯氰菊酯的代谢途径分析(30970099,2010-2013年)

9)  国家自然科学基金项目:Pseudomonas sp. S113 抗磺酰脲乙酰乳酸合酶基因克隆和抗性研究(30500010, 2005-2008年)

10) 科技部农业科技成果转化资金项目:农田土壤六六六和滴滴涕残留生物修复菌剂的中试与示范(2009GB23600516,2009-2011年)

11) “十二五”农村领域科技计划项目子课题:农田复合农药污染微生物修复技术研究(2012AA101403-4,2012-2016年)

12) “十二五”农村领域科技计划项目子课题:杀虫剂农药残留降解新型复合菌制剂的创制(2013AA102804C,2013-2017年)

13) “十二五”农村领域科技计划项目子课题:南方平原稻作农区化学农药面源污染综合防控关键技术研究与示范(2012BAD15B03, 2012-2016年)

14) 中央高校基本科研业务费自主创新重点研究项目:副球菌FLY-8降解氯乙酰胺类除草剂途径及分子机制研究(KYZ201122, 2011年-2014年)

15) 江苏省自然科学基金项目:“菊酯降解菌菊酯降解酶纯化及其基因克隆”(BK2008331,2008-2010)

16) 江苏省自然科学基金项目:“菊酯降解菌菊酯降解酶纯化、特性研究及其基因克隆”(BK2011066, 2011年-2014年)

近年来获得专利情况:

1)  何健,李顺鹏,沈晶晶,黄星,聂志娟 乙酰羟酸合酶抑制剂类除草剂抗性基因ilvBN,专利号:ZL 200910029119

2)  何健,李顺鹏,张隽,殷金岗,杭宝剑 降解乐果、氯苯胺灵和敌稗的酰胺酶基因dimtH及其编码的蛋白质及其应用,专利号: ZL201110208381.9,江苏省百件优秀专利

3)  何健,李怡,陈青,李顺鹏 酰胺酶基因 cmeH 及其编码蛋白质及其应用,专利号:ZL201210227768.3,江苏省百件优秀专利

4)  李顺鹏,何健,杭宝剑 噻吩磺隆水解酶基因tsmE及其应用,专利号:ZL20111020744.2, 国际公布号:WO 2013/013585 A1,美国专利号14/23484,江苏省百件优秀专利

5)  李顺鹏,何健,王保战,郭鹏,李恋,杭宝剑 拟除虫菊酯类杀虫剂水解酶基因,专利号:ZL200810243899.4

6)  何健,李怡,陈青,李顺鹏 一种氯代乙酰胺类除草剂降解菌及其生产的菌剂和应用,申请号:201210228772.1

7)  何健,陈青,李怡,闫新,蒋建东,洪青,黄星,李顺鹏,朱建春 一种加氧酶基因caceO及其编码的蛋白和应用,专利号:ZL201310182539.9,国际申请号:PCT/CN2014/077431.

8)  何健,蔡舒,蔡天明,陈立伟,施超 角度双加氧酶基因dpeA1A2及其应用,专利号:ZL201510855533.2

9)  何健, 王成红, 施超, 陈青, 李顺鹏 一种双加氧酶基因pbaAaAbAcAd及其编码的蛋白质和应用,专利号:ZL201310696034.4

10) 何健,倪海燕,李娜,贺芹,郑金伟,朱建春,洪青 硝基还原酶基因pnr及其编码的蛋白和应用,专利号:ZL201610046506.5

11) 何健,倪海燕,李娜,贺芹,朱建春 硝基还原酶基因lnr及其编码的蛋白和应用,专利号: ZL 2017104191961

12) 何健,褚翠伟,赵家栋,朱建春,蒋建东,洪青 一个双组份的杀草丹降解酶体系及其编码基因和应用,专利号:ZL201610839674.X

13) 何健,李娜,姚利,丁德龙,陶青 一个龙胆酸双加氧酶及其编码基因和应用,专利号: ZL201711069144.2

14) 何健, 李娜,姚利,丁德荣,陶青,陈乐,刘斌,彭乾 麦草畏中间产物3,6-二氯龙胆酸脱氯酶DsmH2及其编码基因的应用,专利号:ZL201810242125.3

15) 何健,姚利,贾兴军,谢香庭,吴业春,陶青,丁德荣 除草剂耐受性蛋白质、其编码基因及用途(DMT66),专利号:ZL201410806871.2

16) 何健,姚利,贾兴军,谢香庭,吴业春,陶青,丁德荣 除草剂耐受性蛋白质、其编码基因及用途(DMT50),专利号: ZL201410810953.4

17) 何健,姚利,贾兴军,谢香庭,吴业春,陶青,丁德荣,除草剂耐受性蛋白质、其编码基因及用途(MTHFR66),专利号:ZL201610440763.7

18) 何健,刘斌,彭乾,陶青,肖翔,鲍晓明 除草剂耐受性蛋白质、其编码基因及用途(SULE突变),专利号:ZL201810124124.9

近年以第一作者和通讯作者发表科研论文情况:(* 通讯作者)

1)  Xu D, Gao Y, Sun B, Ran T, Zeng L, He J, He Jian*, Wang W*. Pyrethroid carboxylesterase PytH from Sphingobium faniae JZ-2: structure and catalytic mechanism. Appl Environ Microbiol. 2020 Jun 2;86(12):e02971-19. doi:  10.1128/AEM.02971-19.

2)  Shigang Yao, Le Chen, Zhou Yang, Li Yao, Jianchun Zhu, Jiguo Qiu, Guoxiang Wang, He Jian*. The properties of 5-methyltetrahydrofolate dehydrogenase (MetF1) and its role in the tetrahydrofolate (THF)-dependent dicamba demethylation system in Rhizorhabdus dicambivorans Ndbn-20. Journal of Bacteriology 2019 JB.00096-19. doi: 10.1128/JB.00096-19.

3)  Jiguo Qiu, Lingling Zhao, Siqiong Xu, Qing Chen, Le Chen, Bin Liu, Qing Hong, Zhenmei Lu, He Jian*. Identification and characterization of a novel pic gene cluster responsible for picolinic acid degradation in Alcaligenes faecalis JQ135. Journal of Bacteriology 2019 JB.00077-19. doi: 10.1128/JB.00077-19.

4)  Jiguo Qiu, Yanting Zhang, Shigang Yao, Hao Ren, Meng Qian, Qing Hong, Zhenmei Lu*, and He Jian*. Novel 3,6-dihydroxypicolinic acid decarboxylase mediated picolinic acid catabolism in Alcaligenes faecalis JQ135. Journal of Bacteriology 2019 DOI: 10.1101/457895/JB.00665-18.

5)  Li Na, Yao Li, He Qin, Qiu Jiguo, Cheng Dan, Ding Derong, Tao Qing, He Jian*, Jiang Jiandong. The catabolism of 3,6-dichlorosalicylate is initiated by the cytochrome P450 monooxygenase DsmABC in Rhizorhabdus dicambivorans Ndbn-20. Appl Environ Microbiol., 2018 Jan 31;84(4). pii: e02133-17. doi: 10.1128/AEM.02133-17. Print 2018 Feb 15.

6)  Li Na, Tong R L, Yao L, Chen Q, Yan X, Ding DR, Qiu JG, He Jian*. Roles of two glutathione-dependent 3,6-dichlorogentisate dehalogenases in Rhizorhabdus dicambivorans Ndbn-20 in the catabolism of the herbicide dicamba [J]. Appl Environ Microbiol., 2018 Aug 17;84(17). pii: e00623-18. doi: 10.1128/AEM.00623-18. Print 2018 Sep 1.

7)  Qiu J, Liu B, Zhao L, Zhang Y, Cheng D, Yan X, Jiang J, Hong Q, He Jian*. A novel degradation mechanism for pyridine derivatives in Alcaligenes faecalis JQ135 [J]. Appl Environ Microbiol., 2018, 84 (15): e00910-18.

8)  Cai Shu, Chen Li-Wei, Ai Yu-chun, Qiu Ji-Guo, Wang Cheng-Hong, Shi Chao, He Jian*, Cai Tian-Ming*,Degradation of diphenyl ether in Sphingobium phenoxybenzoativorans SC_3 is initiated by a novel ring-cleavage dioxygenase, Appl Environ Microbiol., DOI: 10.1128/AEM.00104-17 May 2017 Volume 83 Issue 10 e00104-17.

9)  Yao L, Yu L-L, Zhang J-J, Xie X-T, Tao Q, Yan X, Hong Q, Qiu J-G, He Jian*, DingD-R. A tetrahydrofolate-dependent methyltransferase catalyzing the demethylation of dicamba in Sphingomonas sp. strain Ndbn-20. Appl Environ Microbiol., 2016, 82, 5621–5630.

10) Hang Bao-Jian#, Hong Qing#, Xie Xiang-Ting, Huang Xing, Wang Cheng-Hong, He Jian*, and Li Shun-Peng. SulE, a sulfonylurea herbicide de-esterification esterase from Hansschlegelia zhihuaiae S113. Appl Environ Microbiol., 2012, 78(6): 1962–1968.

11) Zhang Jun#, Yin Jin-Gang#, Hang Bao-Jian#, Cai Shu, He Jian*, Zhou Shun-Gui*, and Li Shun-Peng. Cloning of a novel arylamidase gene from Paracoccus sp. FLN-7 that hydrolyzes amide pesticides. Appl Environ Microbiol., 2012, 78(6):4848–4855.

12) Wang Bao-zhan, Guo Peng, Hang Bao-jian, Li Lian, He Jian*, and Li Shun-peng Cloning of a novel pyrethroid-hydrolyzing carboxylesterase gene from Sphingobium sp. strain JZ-1 and characterization of the gene product. Appl Environ Microbiol., 2009, 75(17): 5496–5500.

13) Wang Cheng-hong, Chen Qing, Wang Rui, Shi Chao, Yan Xin, He Jian*, Hong Qing* and Shunpeng Li. A Novel angular dioxygenase gene cluster, encoding 3-phenoxybenzoate 1’, 2’ -dioxygenase in Sphingobium wenxiniae JZ-1. Appl Environ Microbiol., 2014, 80(13): 3811–3818.

14) Chen Qing, Wang Cheng-Hong, Deng Shi-Kai, Wu Ya-Dong, Li Yi, Yao Li, Jiang Jian-Dong, Yan Xin, He Jian*, Shun-Peng Li. A novel three-component rieske non-heme iron oxygenase (RHO) system catalyzing the N-Dealkylation of chloroacetanilide herbicides in Sphingomonads DC-6 and DC-2. Appl Environ Microbiol., 2014, 80(13): 5078–5085.

15) Mengyao Shenga, Bin Liua, Jianyi Xua, Qian Penga, Lei Zhangb,c, Kai Chena, *, J He Jian* Cloning of a novel topramezone-resistant 4-hydroxyphenylpyruvate dioxygenase gene and improvement of its resistance through pressure acclimation. Enzyme and Microbial Technology 140 (2020) 109642.

16) Yong Yuan, Ya Tao, Shungui Zhou*, Tian Yuan, Qin Lu, He Jian*. Electron transfer capacity as a rapid and simple maturity index for compost. Bioresour. Technol., 2012, 116: 428–434.

17) Qiu J, Zhang Y, Zhao L, He Q, Jiang J-D, Hong Q, He Jian*. Isolation and characterization of the cotinine-degrading bacterium Nocardioides sp. strain JQ2195 [J]. J Hazard Mater., 2018, (353): 158-165.

18) Liu Bin, Peng Qian, Sheng Mengyao, Hu Shishan, Qian Meng, Fan Ben, He Jian*. Directed evolution of sulfonylurea esterase and characterization of a variant with improved activity. J Agric Food Chem., 2018 Dec 26. doi: 10.1021/acs.jafc.8b06198.

19) Qiu Jiguo, Li Na, Lu Zhenmei, Yang Youjian, Ma Yun, Niu Lili,He Jian*,Liu, Weiping. Conversion of nornicotine to 6-hydroxy-nornicotine and 6-hydroxy-myosmine by Shinella sp. strain HZN7, Appl. Microbiol. Biotechnol., 2016.12.01, 100 (23): 10019~10029.

20) Zhang Jun#, Jin-Wei Zheng#, Bin Liang, Cheng-Hong Wang, Ying-Ying Ni, Shu Cai, He Jian*, Shun-Peng Li. Biodegradation of chloroacetamide herbicides by Paracoccus sp. FLY-8. J. Agric. Food. Chem., 2011, 59(9): 4614-21.

21) Nie Zhi-Juan#, Hang Bao-Jian#, Cai Shu, Xie Xiang-Ting, J He Jian*, Li Shun-Peng. Degradation of cyhalofop-butyl (CyB) by Pseudomonas azotoformans strain QDZ-1, and cloning of a novel gene encoding a CyB-hydrolyzing esterase. J. Agric. Food. Chem., 2011, 59(9): 4614-4621.

23) Mengyao Sheng1, Zhou Yang1, Xiaojun Yang2, Jianyi Xu1, Jiguo Qiu1, He Jian* and Shanlian Qiu,* Niastella caeni sp. nov., isolated from activated sludge Int. J. Syst. Evol. Microbiol. DOI 10.1099/ijsem.0.004017.

24) Bin Liu, XiaojunYang, Mengyao Sheng, Zhuo Yang1, Jiguo Qiu, Chenghong Wang, He Jian*. Sphingobacterium olei sp. nov., isolated from oil-contaminated soil. Int. J. Syst. Evol. Microbiol. 2020;70:1931–1939 DOI 10.1099/ijsem.0.004000 (一标).

25) Qian Peng, Mengyao Sheng, Zhou Yang, Haiyan Ni, Qinfen Li, Yi Li, He Jian*. Extensimonas perlucida sp. nov., isolated from sludge. Current microbiology. DOI 10.1007/s00284-020-01911-w.

26) Ni Haiyan, Li Na, Qiu JG, Chen Q*, He Jian*. Biodegradation of pendimethalin by Paracoccus sp. P13 [J]. Curr. Microbiol., 2018, 75(8): 1077-1083.

27) Yao, L., Zhang, J. J., Yu, L. L., Chen, Q., Zhu, J. C., He Jian*., Ding, D. R*. 2016. Rhizorhabdus dicambivorans sp. nov., a dicamba degrading bacterium isolated from compost. Int. J. Syst. Evol. Microbiol., 66:3317-3323.

28) Qiu Jiguo,Zhang Junjie,Zhang Yanting,Wang Yuhong,Tong Lu,Hong Qing,He Jian*. Biodegradation of picolinic acid by a newly isolated bacterium Alcaligenes faecalis strain JQ135. Curr. Microbiol., DOI: 10.1007/s00284-017-1205-2

29) Li Na, Chen Tao, Cheng Dan, Xu Xun-Jun and He Jian*. Chitinophaga sedimenti sp. nov., isolated from sediment. Int. J. Syst. Evol. Microbiol., 2017;67:3485-3489 DOI 10.1099/ijsem.0.002150.

30) Yao, L., Jia, X. J., Zhao, J. D., Cao, Q., Xie, X. T., Yu, L. L., He Jian*, Tao, Q. 2015. Degradation of the herbicide dicamba by two sphingomonads via different demethylation mechanisms. Int. Biodeterior. Biodegrad., 104:324-332.

31) Yang You-Jian, Zhang Yan-Ting, Chen Guo-Qiang, Cheng Dan, Qiu Ji-Guo, Qin He* and He Jian* Paenibacillus shunpengii sp. nov., isolated from farmland soil. Int. J. Syst. Evol. Microbiol., 2018; 68:211–216. DOI 10.1099/ijsem.0.002484.

32) Peng Guo, Bao-Zhang Wang, Bao-Jian Hang, Lian Li, SW Ali, He Jian*, Shun-Peng Li. Pyrethroid-degrading Sphingobium sp. JZ-2 and the purification and characterization of a novel pyrethroid hydrolase. Int. Biodeterior. Biodegrad., 2009, 63(8): 1107–1112.

33) Bao-Zhan Wang, Yun Ma, Wei-You Zhou, Jin-Wei Zheng, Jian-Chun Zhu, He Jian* and Shun-Peng Li. Biodegradation of synthetic pyrethroids by Ochrobactrum tritici strain pyd-1. World J. Microbiol. Biotechnol., 2011, 27: 2315–2324.

34) Bao-Zhan Wang, Peng Guo, Jin-Wei Zheng, Bao-Jian Hang, Lian Li, He Jian*, and Shun-Peng Li. Sphingobium wenxiniae sp. nov., a synthetic pyrethroids (SPs)-degrading bacterium isolated from activated sludge in a SPs-manufacturing wastewater treatment facility. Int. J. Syst. Evol. Microbiol., 2011, 61(8): 1776–1780.

35) Jun Zhang, Jin-Wei Zheng, Bao-Jian Hang, Ying-Ying Ni, He Jian*, and Shun-Peng Li. Rhodanobacter xiangquanii sp. nov., a novel anilofos-degrading bacterium isolated from a wastewater treating system. Curr. Microbiol., 2011, 62: 645–649.

36) Lian Li, Jin-Wei Zheng, Bao-Jian Hang, Nina V. Doronina, Yuri A. Trotsenko, He Jian*, and Shun-Peng Li. Methylopila jiangsuensis sp. nov., a novel aerobic facultatively methylotrophic bacterium. Int. J. Syst. Evol. Microbiol., 2011, 61(8): 1561–1566.

37) Xin-Yan Yu#, Yong-Feng Li#, Jin-Wei Zheng, Yi Li, Lian Li, He Jian*, and Shun-Peng Li. Comamonas zonglianii sp. nov., isolated from phenol-contaminated soil. Int. J. Syst. Evol. Microbiol., 2011, 61(2): 255–258.

38) Jin-Wei Zheng#, Yi-Guang Chen#, Jun Zhang, Ying-Ying Ni, Wen-Jun Li*, He Jian*, and Shun-Peng Li. Catellibacterium caeni sp. nov., and reclassification of Rhodobacter changlensis Anil Kumar et al. 2007 as Catellibacterium changlense comb. nov. Int. J. Syst. Evol. Microbiol., 2011, 61(8): 1921–1926.

39) Zhi-Fei Lang#, Jing-Jing Shen#, Shu Cai, Juan Zhang, He Jian* and Shun-Peng Li. Expression, characterization and site-directed mutation of a multiple herbicide-resistant acetohydroxyacid synthase (rAHAS) from Pseudomonas sp. Lm10. Curr. Microbiol., 2011, 63: 145–150.

40) Chen B, Huang X, Zheng JW, Li SP, He Jian*. Candida mengyuniae sp. nov., a metsulfuron-methyl-resistant yeast. Int. J. Syst. Evol. Microbiol., 2009(59):1237-1241.  3

41) Peng Guo, Bao-Zhan Wang, Bao-Jian Hang, Lian Li, Shun-Peng Li, and He Jian*. Sphingobium faniae sp. nov., a pyrethroid-degrading bacterium isolated from activated sludge treating wastewater from pyrethroid manufacture. Int. J. Syst. Evol. Microbiol., 2010(60): 408–412.

42) Jun Zhang#, Shu-An Chen#, Jin-Wei Zheng, Shu Cai, Bao-Jian Hang, He Jian*, and Shun-Peng Li. Catellibacterium nanjingense sp. nov., a propanil-degrading bacterium isolated from activated sludge of a wastewater bio-treating system, and emended description of the genus Catellibacterium. Int. J. Syst. Evol. Microbiol., 2012 62: 495–499.

43) Jun Zhang, Jin-Wei Zheng, Byung-Cheol Cho, Chung-Yeon Hwang, Cheng-Xiang Fang*, He Jian* and Shun-Peng Li. Sphingobacterium wenxiniae sp. nov., a novel cypermethrin-degrading bacterium isolated from activated sludge of a waste-water treatment plant. Int. Int. J. Syst. Evol. Microbiol., 2012, 62: 683–687.

44) Zhang Jun, Zhi-Fei Lang, Jin-Wei Zheng, Bao-Jian Hang, Xiao-Qin Duan, He Jian*, and Shun-Peng Li. Sphingobium jiangsuense sp. nov., an m-phenoxybenzoic acid-degrading bacterium isolated from a wastewater treating system. Int. J. Syst. Evol. Microbiol., 2012, 62: 800–805.

45) Li-Na Sun#, Jun Zhang#, Soon-Wo Kwon, He Jian*, Shun-Gui Zhou*, and Shun-Peng Li. Paracoccus huijuniae sp. nov., an amide pesticides-degrading bacterium isolated from activated sludge of a wastewater bio-treating system. Int. Int. J. Syst. Evol. Microbiol., 2013, 63: 1132–1137.

46) Yi Li#, Jun Zhang#, Qing Chen, Gui-Qing Yang, Shu Cai, He Jian*, Shun-Gui Zhou*, and Shun-Peng Li. Dokdonella kunshanensis sp. nov., isolated from activated sludge and emended description of the genus Dokdonella. Int. J. Syst. Evol. Microbiol., 2013, 63: 1519–1523.

47) Li-Na Sun, Jun Zhang, Qing Chen, He Jian*, Qin-Fen Li*, and Shun-Peng Li. Comamonas jiangduensis sp. nov., a biosurfactant-producing bacterium isolated from agricultural soil. Int. J. Syst. Evol. Microbiol., 2013, 63: 2168–2173.

48) Li-Na Sun#, Jun Zhang#, Qing Chen, He Jian*, and Shun-Peng Li. Sphingobacterium caeni sp. nov., isolated from activated sludge. Int. J. Syst. Evol. Microbiol., 2013, 63(6): 2260–2264.

49) Shi-Kai Deng#, Xiao-Mei Ye#, Cui-Wei Chu, Jin Jiang, He Jian*, Jun Zhang*, and Shun-Peng Li. Chryseomicrobium aureum sp. nov., a bacterium isolated from activated sludge. Int. J. Syst. Evol. Microbiol., 2014, 64(8): 2682-2687.

50) Qing Chen, Jun Zhang, Cheng-Hong Wang, Jin Jiang, Soon-Wo Kwon, Li-Na Sun, Wen-Biao Shen and He Jian*. Novosphingobium chloroacetimidivorans sp. nov., a chloroacetamide herbicide–degrading bacterium isolated from activated sludge. Int. J. Syst. Evol. Microbiol., 2014, 64: 2573–2578.

51) Shi-Kai Deng, Guo-Qiang Chen, Qing Chen, Shu Cai, Li Yao, and He Jian*, Shun-Peng Li. Rhodoligotrophos jinshengii sp. nov., a bacterium isolated from activated sludge. Int. J. Syst. Evol. Microbiol., 2014, 64(9): 3325–30.

52) Cai Shu, Cai Tian-Ming, Liu Shi-Yang, Yang Qian, He Jian*, Chen Li-Wei *, Hu Jiang. Biodegradation of N-methylpyrrolidone by Paracoccus sp. NMD-4 and its degradation pathway. Int. Biodeterior. Biodegrad., 2014, 93: 70–77.

53) Wu Ya-Dong #, Deng Shi-Kai #, Shi Chao, Zhu Jian-Chun, He Jian* and Shun-Peng Li. Tahibacter caeni sp. nov., isolated from activated sludge. Int. J. Syst. Evol. Microbiol., 2015, 65: 633–638.

54) Chen Qing, Chen Kai, Ni Haiyan, Zhuang Wen, Wang Hongmei, Zhu Jianchun, He Qin, He Jian*. A novel amidohydrolase (DmhA) from Sphingomonas sp. that can hydrolyze the organophosphorus pesticide dimethoate to dimethoate carboxylic acid and methylamine. Biotechnol. Lett., 2016, Volume 38, Issue 4, pp 703–710

55) Cai Shu, Shi Chao, Zhao Jia-Dong, Cao Qin, He Jian* and Chen Li-Wei *. Sphingobium phenoxybenzoativorans sp. nov., a 2-phenoxybenzoic-acid-degrading bacterium. Int. J. Syst. Evol. Microbiol., 2015, 65, 1986–1991. 01 June 2015

56) Chu Cui-Wei, Chen Qing, Wang Cheng-Hong, Wang Hong-Mei, Sun Zhong-Guan, He Qin, He Jian*, Gu Jin-Gang*. Roseomonas chloroacetimidivorans sp. nov., a chloroacetamide herbicide-degrading bacterium isolated from activated sludge. Antonie van Leeuwenhoek. May 2016, Volume 109, Issue 5, pp 611–618

57) Wang Chenghong, Deng Shikai, Liu Xin, Yao Li, Shi Chao, Jiang Jin, Kwon Soon-Wo, He Jian* and Jiayou Li*. Roseomonas eburnea sp. nov., isolated from activated sludge. Int. J. Syst. Evol. Microbiol., 2016, 66:385–390.


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